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“Shingles? I’m fit
and healthy –
I didn’t think it
would happen to me.
I was in agony
for weeks.”*

Patient portrayal.

*Inspired by real patient stories. Shingles symptoms may vary among patients.1

Don’t underestimate your risk of shingles

90% of people over 50 carry the virus that causes shingles.2†

If you’ve had chickenpox, the virus could reactivate at any time. Your risk increases sharply after 50, as your
immune system is less able to keep the virus dormant.1,3

Even if you are fit and healthy, you could still be at risk of shingles.1

Not everyone at risk will develop shingles.1

Some underlying medical conditions can increase your risk.1

  • down-arrow Diabetes

    People with diabetes are 40% more likely to develop shingles, compared to people without diabetes.4 If you have type 2 diabetes specifically, you could be at almost double the risk, compared to those without diabetes.5  

    Not only may diabetes increase your shingles risk, it can also increase your risk of shingles-related complications, such as long-term nerve pain, and hospitalisation.1,6,7

  • down-arrow Respiratory conditions

    Respiratory conditions and their treatments can weaken the immune system, increasing risk of shingles.8,9

    • Chronic obstructive pulmonary disease increases shingles risk by 40%8
    • Asthma increases shingles risk by 20%8

    The use of steroid medication and oral inhalers, used to treat these conditions, could further increase this risk.10,11

  • down-arrow Heart disease

    Heart disease can increase your risk of shingles by almost 30%, compared to people without heart disease.8

    Shingles may increase your risk of developing a stroke.12*

    *Within 3 months of shingles.12

  • down-arrow Kidney disease

    Kidney disease can weaken the immune system, increasing the risk of developing shingles.8,13 It increases your risk of shingles by 30%, compared to people without kidney disease.8

    Not only this, but if you get shingles, it can have damaging effects on your kidneys, causing your disease to progress faster than it would have without shingles.14

  • down-arrow Cancer

    Cancer and chemotherapy are known for weakening the immune system.1 This puts people with cancer at increased risk of shingles.15
    Someone with cancer who is being treated with chemotherapy can have up to 7x the risk of shingles, compared to those without cancer.15

  • down-arrow Rheumatoid arthritis

    Rheumatic diseases, including rheumatoid arthritis can weaken the immune system – increasing susceptibility to shingles.1,8
    The risk of shingles in people with rheumatoid arthritis is increased by 50%, compared to those without rheumatoid arthritis.8

Don’t let shingles put your life on hold

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Shingles prevention options

LEARN MORE HERE
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Act now – start the discussion with your doctor

download discussion guide

All images across the webpage are patient portrayals.

If you experience any side effects while taking a medicinal product, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. Adverse events should be reported directly to the Cypriot Ministry of Health on the Yellowcard website: Κίτρινη Κάρτα - Υπουργείο Υγείας

Disease awareness information provided by GSK intended for members of the public in Cyprus only. This information is not intended to be a substitute for professional medical advice. Talk to your doctor for more information about shingles.

References
  1. Harpaz R, Ortega-Sanchez IR, Seward JF. Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2008;57(RR-5): 1–30.
  2. Bollaerts K, Riera-Montes M, Heininger U, et al. A systematic review of varicella seroprevalence in European countries before universal childhood immunization:
deriving incidence from seroprevalence data. Epidemiol Infect. 2017;145:2666–2677.
  3. Hales CM, Harpaz R, Ortega-Sanchez I, Bialek SR. Update on recommendations for use of herpes zoster vaccine. MMWR Morb Mortal Wkly Rep. 2014;63(33):729–731.
  4. Huang CT, Lee CY, Sung HY, et al. Association between diabetes mellitus and the risk of herpes zoster: A systematic review and meta-analysis. J Clin Endocrinol Metab. 2022;107:586–597.
  5. Poirrier JE, Meyers JL, Nagar SP, et al. Herpes zoster incidence and burden in adults with type 2 diabetes in the USA: retrospective database analysis. Diabetes Care. 2022;45:2585–2593.
  6. Muñoz-Quiles C, Lopez-Lacort M, Ampudia-Blasco FJ, et al. Risk and impact of herpes zoster on patients with diabetes: A population-based study, 2009–2014. Hum Vaccin Immunother. 2017;13:2606–2611.
  7. Forbes HJ, Bhaskaran K, Thomas S L, et al. Quantification of risk factors for postherpetic neuralgia in herpes zoster patients: A cohort study. Neurology. 2016;87:94–102. 
  8. Marra F, Parhar K, Huang B, Vadiamudi N. Risk factors for herpes zoster infection: A meta-analysis. Open Forum Infect Dis. 2020;7:ofaa005.
  9. Safonova E, Yawn B, Welte T, Wang C. Risk factors for herpes zoster: should people with asthma or COPD be vaccinated? Respir
Res. 2023;24:35
  10. Yang YW, Chen YH, Wang KH et al. Risk of herpes zoster among patients with chronic obstructive pulmonary disease: a population-based study. CMAJ 2011;183:E275–280.
  11. Bloechliger M, Reinau D, Spoendlin J et al. Adverse events profile of oral corticosteroids among asthma patients in the UK: cohort study with a nested case-control analysis. Respir Res 2018;19:75.
  12. Erskine N, Tran H, Levin L, et al. A systematic review and meta-analysis on herpes zoster and the risk of cardiac and cerebrovascular events. PloS One. 2017;12:e0181565.
  13. Ishigami J, Matsushita K. Clinical epidemiology of infectious disease among patients with chronic kidney disease. Clin Exp Nephrol 2019;23:437–447.
  14. Lin SY, Liu JH, Yeh CH, et al. Association between herpes zoster and end stage renal disease entrance in chronic kidney disease patients: a population-based cohort study. Eur J Clin Microbiol Infect Dis. 2014;33:1809–1815.
  15. Habel LA, Ray GT, Silverberg MJ et al. The epidemiology of herpes zoster in patients with newly diagnosed cancer. Cancer Epidemiol Biomarkers Prev. 2013;22:82–90.
  16. Winthrop K, Curtis J, Yamaoka K, et al. Clinical management of herpes zoster in patients with rheumatoid arthritis or psoriatic arthritis receiving tofacitinib treatment. Rheumatol Ther. 2022;9:243–263.